Multiple Sclerosis and Vitamin D: Is there a Link in the Multifactorial Model?

MS is a rare neurodegenerative disease with an immunopathological background. Although, it has rather low global prevalence, can be considered among one of the most common youth disabling disorders that are not related to trauma. It also classified as complex many susceptibility genes incriminated in its etiology and prognosis. In addition, several well identified extensively studied environmental factors implicated vitamin D metabolism & ultraviolet B (UVB) exposure, Epstein Barr virus (EBV) infection, smoking morbid obesity. The infamous relationship between Vitamin been area extensive research aspects; pathophysiology, course, prognosis even response treatment.